How will your role help us transform hope into reality? The Laboratory Animal Resources group at Blueprint Medicines is seeking a highly motivated, extremely organized, and collaborative Animal Care Facility (ACF) Senior Manager to work in a fast-paced environment within a cross-functional team. Laboratory Animal Resources (LAR) at Blueprint Medicines is an organization responsible for providing in-vivo resources to enable drug discovery objectives relevant to pharmacology, DMPK, biopharmaceutics, tolerability, and translational medicine. LAR comprises an internal rodent vivarium, hands-on in-vivo scientific staff, husbandry technicians, and an external attending veterinarian. As ACF Senior Manager, you will be a key team member within the LAR group and the broader Quantitative Translational Pharmacology organization. It will be your responsibility to manage Blueprint’s on-site ACF, including daily operations to support animal husbandry, facility maintenance, compliance with IACUC protocol and EH&S policy, and adherence to standards that are required to maintain AAALAC accreditation. You will work closely with the in vivo pharmacology team to manage the vivarium operations that are required to support fast paced in vivo programs. In this high impact position, you will have the opportunity to lead an important animal laboratory that supports Blueprint’s non-clinical pharmacology programs across various drug discovery and development stages. What will you do? Responsible for day-to-day operational activities associated with Blueprint’s on-site ACF, including managing purchase orders for animals, housing, feed, and all other consumable supplies Works closely with animal husbandry team to manage all daily activities to support animal care Works with IACUC and attending veterinarian (AV) to ensure that animal care and welfare in the ACF is implemented in a manner that meets the high standards required for maintaining accreditation by AAALAC Coordinates regular ACF visits with AV and/or IACUC Contributes to writing and renewal of IACUC animal use protocols, and is responsible for writing, renewal and adherence to all BPMC ACF policies and procedures Works with EH&S team to ensure compliance with all relevant Occupational Health and Safety requirements Works with IACUC and EH&S to ensure the ACF’s continued compliance with all applicable Federal, State and City of Cambridge regulations concerning the use of animals for research and the use of controlled substances Arranges regular maintenance and/or inspection of equipment in ACF, including but not limited to BSCs, grossing stations, anesthesia machines, and animal housing Responsible for all documentation relevant to ACF maintenance, cleaning, inspection, animal care, and training program Responsible for management, orientation, and training on ACF policies, procedures, and electronic software for documentation of animal orders, census, veterinary records, and training programs Partners with Facility Operations Team to ensure maintenance of mechanical equipment and arranges equipment service as needed Works with in vivo pharmacology team to ensure readiness for animal orders, in vivo studies, and organize animal housing space If applicable based on experience, individual may also participate in in vivo/ex vivo activities to support the in vivo pharmacology team This is an on-site position which occasionally requires work during non-business hours and on weekends What minimum qualifications do we require? Bachelor’s degree plus 8 years industry experience or MS plus 5 years of industry experience, including at least 5 years’ experience working with animals 2 years in a vivarium management role What additional qualifications will make you a stronger candidate? Advanced degree in veterinary medicine, animal science, or related field Hands-on experience with performing in-vivo studies in rodents, dosing by various routes of administration, and tissue collection techniques Strong oral and written communication skills, as well as excellent documentation and organizational skills are essential Strong interpersonal and communication skills, with a passion for participating in a fast-paced environment characterized by challenging and rigorous science, and creative thinking Experience with standard software analytical tools including Excel Collaborative with effective listening skills and open, clear, consistent communication abilities American Association of Laboratory Animal Science Laboratory Animal Technician Certification (ALAT, LAT, or LATG) Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism Why Blueprint? At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success. This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap? Equity, Diversity, Inclusion and Affirmative Action At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewardsblueprintmedicines.com. For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement . Blueprint Medicines is a global, fully integrated biopharmaceutical company that invents life-changing medicines. We seek to alleviate human suffering by solving important medical problems in two core focus areas: allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a proven track record of success with two approved medicines, including bringing our medicine to patients with systemic mastocytosis (SM) in the U.S. and Europe. Leveraging our established research, development, and commercial capability and infrastructure, we now aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases including SM and chronic urticaria, breast cancer and other solid tumors. LI-Onsite LI-AQ1